Regenexx FAQs

These procedures are designed to treat common orthopedic conditions and help people avoid surgery using cells from their own body.

A physician in the licensed Regenexx network uses image guidance to inject customized concentrations of the patient’s own cells, from either blood or bone marrow concentrate, into the precise area(s) of injury.

Deciding if a nonsurgical procedure is right for you starts with learning your candidacy for treatment.

Schedule a consultation with a physician in the licensed Regenexx network who will evaluate your condition or injury, explain your candidacy for a nonsurgical procedure, and answer your questions.

Some reasons patients choose to learn their candidacy for a procedure include:

• Struggling with a condition that’s not improving
• Unsure about a diagnosis or treatment plan from another doctor
• Desire to avoid or put off orthopedic surgery, prefer a treatment that is less invasive than surgery
• Desire to use their own cells for treatment and avoid implants, permanent hardware, grafts, and/or removal of tissue

Although we are able to provide you with results data for procedures and your specific candidacy for a procedure, no one can guarantee a full restoration of your body to the way it was prior to injury.

Like all medical procedures, procedures using Regenexx injectates have a success and failure rate. You can review what patients report for pain reduction and joint function improvement for up to six years post-procedure by exploring Patient Results.

Using the U.S. Department of Health and Human Services (HHS and OHRP) guidelines for complications reporting, complications to date have been in the mild to moderate category and rare.

• Mild: requires no medical treatment. For example transient swelling.
• Moderate: requires treatment. For example, opting for a treatment other than a procedure using Regenexx lab processes if it failed.

We have published an extensive safety and complications tracking study of bone marrow concentrate, which contains adult stem cells, in patients. This study did not show any serious procedure-related complications and it did not show that any patient developed a cancer related to bone marrow concentrate use. View our Safety Paper.

Procedures using Regenexx SCP and PL injectates start with a basic blood draw. Regenexx SD injectate, a bone marrow concentrate procedure, requires a bone marrow aspirate with local anesthetic. A bone marrow aspirate is significantly less invasive than a bone marrow biopsy. Some patients are given an oral sedative to help to ease anxiety and relax the muscles prior to the bone marrow draw.

Procedures are performed with comfort considerations for the patient. Local anesthesia is used to numb the area(s) of treatment. After a procedure, the joint and injection site(s) may feel sore. Your physician may prescribe pain medicine or recommend acetaminophen. You will be asked to keep the joint as still as possible for 30-60 minutes after the procedure and limit activity on the joint for the first day post-procedure. Your physician may also recommend a brace, wrap, or walking boot to support the area treated.

Generally, patients return to normal daily activities as tolerated. Most patients resume light activities after 5 to 7 days and return to sports at 6 to 8 weeks. Further improvement may continue over several months. Your physician will discuss what post-procedure may be like for you based on your specific condition or injury and the recommended procedure.

Some patients are able to have more than one area treated at the same time. This is on a case-by-case basis and determined by several factors including: evaluation and recommendation of the physician, the amount of blood or bone marrow that would need to be drawn and concentrated to treat multiple areas of injury, and the overall comfort of the patient.

A procedure using Regenexx SCP injectate is a blood based procedure. SCP means “Super Concentrated Platelets” and is a type of highly-concentrated platelet rich plasma (PRP) procedure.

A procedure using Regenexx SD injectate is a bone marrow concentrate (BMC) based procedure; bone marrow concentrate contains the patient’s own stem cells. SD means “Same Day” as the cells are harvested, highly-concentrated, and reinjected on the same day.

Regenexx does not call procedures using Regenexx SD injectate “stem cell procedures.” Unfortunately, that term has been co-opted by sellers of products which are manufactured from birth tissue (typically amniotic fluid or membrane), and then bottled, labeled as “stem cells”, and then shipped nationwide.

A procedure using Regenexx SD injectate is a bone marrow concentrate (BMC) based procedure; bone marrow concentrate contains the patient’s own stem cells. This procedure uses customized concentrations of the patient’s own cells for treatment and is specific to their individual condition or injury needs.

You can review what patients report for pain reduction and joint function improvement for up to six years post-procedure by exploring our Patient Results.

There are many factors that contribute to the effects of a procedure over time including: specific condition or injury treated, severity of the condition or injury, candidacy for procedure, and the lifestyle and activity levels of the patient. A physician in the licensed Regenexx network will discuss what post-procedure may be like for you based on your specific condition or injury and the recommended procedure.

Your physician may recommend additional types of conservative care to support your post procedure recovery. These care recommendations may include: physical therapy, myofascial release, home exercises, and bracing or taping.

These procedures are customized for each patient and their specific injury needs. The price and any insurance or benefits you may have are reviewed during your consultation appointment. Generally, platelet procedures using Regenexx SCP injectate cost considerably less than procedures using bone marrow concentrate (Regenexx SD injectate).

Medical insurance plans may cover evaluation appointments, diagnostic testing (if recommended), imaging (X-ray or MRI), physical therapy (if recommended) and bracing (if recommended). While other employer specific benefits typically cover the procedure using Regenexx lab processing.

Your plan paperwork or benefits documents can help verify any coverage or employer specific benefits you may have as well as in-network benefits for specialist services within your plan.

Yes, some employers do include Regenexx Benefits for their employees. If your employer includes Regenexx Benefits you will find more details about your specific plan in your employee benefits documents. You may have received a Regenexx benefits card and/or welcome letter in the mail and your employer will have a Regenexx Benefits website link where you can access additional information about your specific Regenexx Benefits. You can also search to see if your employer or group offers Regenexx Benefits, here.

Unfortunately, neither Medicare nor Medicaid choose to cover regenerative procedures at this time.

Other providers may offer their patient less costly methods of treatment requiring less time from the provider, basic medical equipment, and offering little to no customization.

Other clinics may also:

• Restrict patient access to a board-certified physician.
• Allow non-physician practitioners to handle evaluations and/or procedures.
• Base recommendations solely on limited information, such as verbal details or imaging.
• Use off-the-shelf pharmaceuticals or drugs instead of customized injectates.
• Offer standardized approaches rather than customizing the dosage for individual injuries or conditions.
• Use less concentrated injectates.
• Perform injections without image guidance (blind injections).
• Provide limited follow-up care or post-procedure support.

An injection-based procedure produces a micro injury. After a procedure, the joint and injection site(s) may feel sore.

Using the U.S. Department of Health and Human Services (HHS and OHRP) guidelines for complications reporting, complications to date have been in the mild to moderate category and rare.

• Mild: requires no medical treatment. For example transient swelling.
• Moderate: requires additional treatment. For example, opting for a treatment other than a procedure using Regenexx lab processing.

We have published an extensive safety and complications tracking study of bone marrow concentrate, which contains adult stem cells, in patients. This study did not show any serious BMC related complications. View our Safety Paper.